883199-05-1Relevant academic research and scientific papers
Study on the reactions of ethyl 4,4,4-trifluoro-3-oxobutanoate with arylidenemalononitriles
Li, Xianfu,Song, Liping,Xing, Chunhui,Zhao, Jingwei,Zhu, Shizheng
, p. 2255 - 2263 (2006)
In the presence of a catalytic amount of NEt3, ethyl 4,4,4-trifluoro-3-oxobutanoate 1 reacted readily with arylidenemalononitriles 2 in ethanol at room temperature. It gave two products 2-trifluoromethyl-3,4- dihydro-2H-pyran derivatives 3 and
PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGIUR2 ANTAGONISTS
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Page/Page column 25; 26; 34, (2010/11/29)
The present invention relates to compounds of formula (I), a process for the manufacture thereof, pharmaceutical compositions containing them, and their use for treating CNS disorders:wherein A, B, X, Y, R1, R2, R3 and R4 are as defined in the description and claims.
