883199-55-1Relevant academic research and scientific papers
Cobalt carbonyl-catalyzed carbonylation of functionalized aziridines to versatile β-lactam building blocks
Piens, Nicola,Van Hecke, Kristof,Vogt, Dieter,D'Hooghe, Matthias
supporting information, p. 4816 - 4821 (2017/07/10)
The Co2(CO)8-catalyzed carbonylation of different classes of non-activated aziridines with diverse substitution patterns was investigated. Special attention was devoted to selectivity issues and reaction optimization. This study resu
Systematic study of halide-induced ring opening of 2-substituted aziridinium salts and theoretical rationalization of the reaction pathways
D'Hooghe, Matthias,Catak, Saron,Stankovic, Sonja,Waroquier, Michel,Kim, Yongeun,Ha, Hyun-Joon,Van Speybroeck, Veronique,De Kimpe, Norbert
experimental part, p. 4920 - 4931 (2010/10/03)
The ring-opening reactions of 2-alkyl-substituted l,1-bis(arylmethyl)- and 1-methyl-1-(l-phenylethyl)aziridinium salts with fluoride, chloride, bromide and iodide in acetonitrile have been, evaluated for the first: time in a systematic way. The reactions
A new approach towards 2-amino-1-aryloxy-3-methoxypropanes from 1-arylmethyl-2-(bromomethyl)aziridines
D'Hooghe, Matthias,Waterinckx, Alex,Vanlangendonck, Tim,De Kimpe, Norbert
, p. 2295 - 2303 (2007/10/03)
1-Arylmethyl-2-(bromomethyl)azirdines were converted into the corresponding 2-(aryloxymethyl)aziridines upon treatment with the appropriate potassium phenoxides in DMF/acetone in excellent yields, followed by regioselective ring opening towards N,N-di(ary
