883221-06-5Relevant academic research and scientific papers
Methodology for the synthesis of 1,2-disubstituted arylnaphthalenes from α-tetralones
Moleele, Simon S.,Michael, Joseph P.,De Koning, Charles B.
, p. 2831 - 2844 (2006)
α-Tetralones were initially converted into 1-bromo- dihydronaphthalene-2-carbaldehydes and 1-bromo-naphthalene-2-carbaldehydes. These precursors were then subjected to Suzuki coupling reactions to afford 1,2-disubstituted aryldihydronaphthalenes and 1,2-disubstituted arylnaphthalenes, respectively. The former products were oxidized with DDQ to give 1,2-disubstituted arylnaphthalenes.
