883244-63-1

Upstream product

• 91-00-9 Benzhydrylamine 
• 620179-31-9 N-(α-bromo-α-phenylacetyl)-(S)-proline methyl ester 

Downstream Products

• 1399803-56-5 N-[(R)-α-phenyl-N,N-(dibenzyl)glycinyl]-(S)-2-(hydroxydiphenylmethyl)pyrrolidine 
• 1399803-59-8 N-((R)-N,N-dibenzyl-2-amino-2-phenylethyl)-(S)-2-(hydroxydiphenylmethyl)pyrrolidine 

Relevant academic research and scientific papers

Discovery of dipeptide-derived catalysts for the enantioselective addition of dimethylzinc to aldehydes

A new class of modular chiral catalysts derived from various amino acid-L-Pro dipeptides was prepared, and the catalysts were tested for their ability to catalyze the enantioselective addition of dimethylzinc to aromatic aldehydes. Dipeptides derived from L-Asp-L-Pro were identified as effective catalysts for the addition at room temperature with up to 97:3er and 95% yield.

Asymmetric dehydration of β-hydroxy esters and application to the syntheses of flavane derivatives

Catalytic asymmetric dehydration of β-aryl or alkyl substituted β-hydroxy esters via kinetic resolution has been investigated. A brief survey of 10 different chiral ligands is conducted to examine the effects of chiral ligand structure on selectivity of t