620179-31-9

Upstream product

• 4870-65-9 2-bromophenylacetic acid 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 19078-72-9 bromo(phenyl)acetyl chloride 

Downstream Products

• 883244-63-1 N-[(R)-α-phenyl-N-(diphenylmethyl)glycinyl] (S)-proline methyl ester 
• 1101850-32-1 (S)-N-{(R)-2-[bis(m-fluorophenyl)methylamino]-2-phenylethyl}prolinol 
• 1101850-31-0 (S)-N-{(R)-2-[bis(p-fluorophenyl)methylamino]-2-phenylethyl}prolinol 
• 1101850-33-2 (S)-N-{(R)-2-[bis(p-methylphenyl)methylamino]-2-phenylethyl}prolinol 
• 1101850-30-9 (S)-N-{(R)-2-[bis(p-chlorophenyl)methylamino]-2-phenylethyl}prolinol 
• 925461-15-0 (R)-α-phenyl-α-(1-piperidinyl)acyl-L-proline methyl ester 
• 1374558-48-1 N-benzyl-N-(2-phenethyl)-D-phenylglycinyl-L-proline methyl ester 
• 1374558-47-0 N-benzyl-N-methyl-D-phenylglycinyl-L-proline methyl ester 
• 124674-43-7 (RS) pyrrolo <1,2a> 3-phenyl 1,4-diketopiperazine 
• 1399803-62-3 N-((R)-N,N-dinaphthylmethyl-2-amino-2-phenylethyl)-(S)-2-(hydroxydiphenylmethyl)pyrrolidine 
• 1399803-59-8 N-((R)-N,N-dibenzyl-2-amino-2-phenylethyl)-(S)-2-(hydroxydiphenylmethyl)pyrrolidine 
• 1399803-56-5 N-[(R)-α-phenyl-N,N-(dibenzyl)glycinyl]-(S)-2-(hydroxydiphenylmethyl)pyrrolidine 

Relevant academic research and scientific papers

Asymmetric synthesis of 3,4,6-trisubstituted 2,5-diketopiperazines by using dynamic kinetic resolution of α-bromo tertiary acetamides

A new and efficient method for the asymmetric synthesis of 3,4,6-trisubstituted 2,5-diketopiperazines has been developed. The dynamic kinetic resolution of L-amino-acid-derived α-bromo tertiary amides in the nucleophilic substitution reaction with p-anisi

Stereoselective syntheses of tri- and tetrapeptide analogues by dynamic resolution of α-halo amides in nucleophilic substitution

Dynamic resolution of α-bromo and α-chloro acetamides in nucleophilic substitution with amine nucleophiles in the presence of TBAI has been investigated for stereoselective syntheses of tri- and tetrapeptide analogues. Mechanistic investigations suggest t

Asymmetric nucleophilic substitution of α-bromo amides via dynamic kinetic resolution for the preparation of dipeptide analogues

Asymmetric nucleophilic substitution reactions of α-bromo α-aryl acetamides derived from L-amino acids are described. The simple and practical syntheses of dipeptide analogues have been developed with dibenzylamine, TBAI and a base to provide 2a-2n and 4