88338-70-9

Basic information

• Product Name: 7-({5-[2-(diethylamino)ethyl]-1,2,4-oxadiazol-3-yl}methyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
• CAS NO: 88338-70-9
• Molecular Formula: C₁₆H₂₃N₇O₃
• Molecular Weight: 361.3989
• Mol File: 88338-70-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 579.659°C at 760 mmHg
• Flash Point: 304.367°C
• Density: 1.393g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 7-({5-[2-(diethylamino)ethyl]-1,2,4-oxadiazol-3-yl}methyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-({5-[2-(diethylamino)ethyl]-1,2,4-oxadiazol-3-yl}methyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(88338-70-9)
• EPA Substance Registry System: 7-({5-[2-(diethylamino)ethyl]-1,2,4-oxadiazol-3-yl}methyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione(88338-70-9)

Safety Data

• Hazardous Substances Data: 88338-70-9(Hazardous Substances Data)

Upstream product

• 88338-72-1 2-(theophyllin-7-yl)-O-acroylacetamidoxime 
• 109-89-7 diethylamine 
• 88338-75-4 7-[{5-(2-chloroethyl)-1,2,4-oxadiazol-3-yl}-methyl]-theophylline 
• 22270-11-7 2-(theophyllin-7-yl)-acetamidoxime 
• 5515-83-3 ethyl 3-(diethylamino)propionate 

Relevant articles and documents

Theophyllinyl-alkyl-oxadiazoles, process for the preparation thereof and pharmaceutical compositions containing same

Antitussive compounds of the formula I STR1 or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or STR2 R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula STR3 wherein R stands for hydrogen or methyl, n is 0 to 3, R2 stands for hydrogen or straight or branched chain alkyl, R3 stands for hydrogen or straight or branched chain alkyl or, R2 and R3 together with the nitrogen atom may form a 5-6 membered ring, which ring can optionally contain an oxygen or a second nitrogen atom, the latter, optionally substituted by methyl or, R1 can stand for a phenyl group of the formula wherein R4 and R5 represent independently hydrogen, chlorine, hydroxy, methoxy, ethoxy, methyl or amino or, R1 may further stand for hydroxy, in this case the compound of the formula I may exist according to the conditions in the form of tautomers of the formula Ia STR4 and R1 may further stand for benzyl, 2,2-diphenylethyl or theophyllin-7-yl-methyl.