88354-10-3Relevant academic research and scientific papers
Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies
El-Azab, Adel S.,Abdel-Aziz, Alaa A.-M.,Abou-Zeid, Laila A.,El-Husseiny, Walaa M.,ElMorsy, Ahmad M.,El-Gendy, Manal A.,El-Sayed, Magda A.-A.
, p. 989 - 998 (2018/06/07)
A new series of NSAID thioesters were synthesized and evaluated for their in vitro antitumor effects against a panel of four human tumor cell lines, namely: HepG2, MCF-7, HCT-116 and Caco-2, using the MTT assay. Compared to the reference drugs 5-FU, afati
PHOTOLYSIS OF 2-ARYLOXY- OR 2-ARYLTHIO-1,3-BENZODIOXAN-4-ONES
Diaz-Mondejar, M. Rosa,Miranda, Miguel A.
, p. 1125 - 1131 (2007/10/02)
Photolysis of 1,3-benzodioxan-4-ones 3b and 4a gives mainly products derived from photorearrangement, photoreduction and/or photosolvolysis.These results closely parallel those obtained by irradiation of the isomeric open-chain compounds 1b and 2a.A mechanism involving the intermediacy of radical pairs A and B, generated by successive homolysis of the aryloxy- or arylthio-carbon and carbonyl-oxygen bonds, is proposed.
