883547-84-0 Usage
Uses
Used in Pharmaceutical Industry:
[3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE is used as a chemical intermediate for the development of new drugs due to its unique structure and properties. It may contribute to the creation of novel therapeutic agents for various medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, [3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE is used as a building block for the synthesis of new agrochemical products, such as pesticides and herbicides. Its unique structure may provide enhanced efficacy and selectivity in controlling pests and weeds.
It is important for researchers and chemists to further study and understand the potential uses and effects of [3-(2-CHLORO-PHENOXY)-PROPYL]-METHYL-AMINE to fully harness its potential in these and other industries.
Check Digit Verification of cas no
The CAS Registry Mumber 883547-84-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,3,5,4 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 883547-84:
(8*8)+(7*8)+(6*3)+(5*5)+(4*4)+(3*7)+(2*8)+(1*4)=220
220 % 10 = 0
So 883547-84-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H14ClNO/c1-12-7-4-8-13-10-6-3-2-5-9(10)11/h2-3,5-6,12H,4,7-8H2,1H3
883547-84-0Relevant academic research and scientific papers
Improved model of lanosterol 14α-demethylase by ligand-supported homology modeling: Validation by virtual screening and azole optimization
Sheng, Chunquan,Wang, Wenya,Che, Xiaoying,Dong, Guoqiang,Wang, Shengzheng,Ji, Haitao,Miao, Zhenyuan,Yao, Jianzhong,Zhang, Wannian
experimental part, p. 390 - 397 (2010/11/18)
Lanosterol 14α-demethylase (CYP51) is an important target for antifungal drugs. An improved three-dimensional model of CYP51 from Candida albicans (CACYP51) was constructed by ligand-supported homology modeling and molecular dynamics simulations. The accuracy of the constructed model was evaluated by its performance in a small-scale virtual screen. The results show that known CYP51 inhibitors were efficiently discriminated by the model, and it performed better than our previous CACYP51 model. The active site of CACYP51 was characterized by multiple copy simultaneous search (MCSS) calculations. On the basis of the MCSS results, a series of novel azoles were designed and synthesized, and they showed good in vitro antifungal activity with a broad spectrum. The MIC80 value of four of these compounds against C. albicans is 0.001 μgmL-1, indicating that they are promising leads for the discovery of novel antifungal agents.
