883554-84-5Relevant academic research and scientific papers
Discovery and Development of a Series of Pyrazolo[3,4- d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
Wang, Yulan,Dai, Yang,Wu, Xiaowei,Li, Fei,Liu, Bo,Li, Chunpu,Liu, Qiufeng,Zhou, Yuanyang,Wang, Bao,Zhu, Mingrui,Cui, Rongrong,Tan, Xiaoqin,Xiong, Zhaoping,Liu, Jia,Tan, Minjia,Xu, Yechun,Geng, Meiyu,Jiang, Hualiang,Liu, Hong,Ai, Jing,Zheng, Mingyue
, p. 7473 - 7488 (2019/09/03)
Alterations of fibroblast growth factor receptors (FGFRs) play key roles in numerous cancer progression and development, which makes FGFRs attractive targets in the cancer therapy. In the present study, based on a newly devised FGFR target-specific scorin
Azoles and azolo-azines via 3-(3-methylbenzofuran-2-yl)-3-oxopropanenitrile
Dawood, Kamal M.,Farag, Ahmad M.,Abdel-Aziz, Hatem A.
, p. 378 - 381 (2007/10/03)
3-(3-Methylbenzofuran-2-yl)-3-oxopropanenitrile (2), a versatile synthon, was prepared and utilised in the synthesis of several azoles and fused azolo-azine derivatives.
