883554-93-6

Usage

Uses

Used in Laboratory Settings:
5-Bromo-2-nitro-benzoic acid methyl ester is used as a synthetic intermediate for various chemical reactions in laboratory settings. Its reactive nature allows for the synthesis of a wide range of compounds, making it a valuable asset in research and development.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Bromo-2-nitro-benzoic acid methyl ester is used as a building block for the synthesis of various drug molecules. Its unique structure and reactivity enable the creation of new compounds with potential therapeutic applications.
Used in Chemical Research:
5-Bromo-2-nitro-benzoic acid methyl ester is employed as a research tool in chemical research, where it is used to study the effects of bromine and nitro groups on the reactivity and properties of benzoic acid esters. This knowledge can be applied to the development of new synthetic methods and the discovery of novel compounds.
Safety Considerations:
Due to its potential health risks upon contact or inhalation, as well as its potential harm to the environment, 5-Bromo-2-nitro-benzoic acid methyl ester should be handled with care. Proper safety measures, such as wearing protective gear and working in a well-ventilated area, should be taken to minimize exposure and ensure the safety of those working with 5-BROMO-2-NITRO-BENZOIC ACID METHYL ESTER.

InChI:InChI=1/C8H6BrNO4/c1-14-8(11)6-4-5(9)2-3-7(6)10(12)13/h2-4H,1H3

Upstream product

• 78238-06-9 methyl ester of 2-nitro-3-methoxy-5-aminobenzoic acid 
• 67-56-1 methanol 
• 585-76-2 m-bromobenzoic acid 
• 6950-43-2 5-bromo-2-nitrobenzoic acid 
• 74-88-4 methyl iodide 
• 78238-13-8 3-methoxy-5-nitrobenzoic acid methyl ester 
• 78238-04-7 2-nitro-3-methoxy-5-acetylaminobenzoic acid 
• 78238-05-8 2-nitro-3-methoxy-5-aminobenzoic acid 
• 78238-03-6 3-methoxy-5-acetylaminobenzoic acid 
• 78238-12-7 3-methoxy-5-nitrobenzoic acid 

Downstream Products

• 1241894-37-0 5-bromo-2-nitrobenzylic alcohol 

Relevant academic research and scientific papers

Chemoselective Probe Containing a Unique Bioorthogonal Cleavage Site for Investigation of Gut Microbiota Metabolism

While metabolites derived from gut microbiota metabolism have been linked to disease development in the human host, the chemical tools required for their detailed analysis and the discovery of biomarkers are limited. A unique and multifunctional chemical probe for mass spectrometric analysis, which contains p-nitrocinnamyloxycarbonyl as a new bioorthogonal cleavage site has been designed and synthesized. Coupled to magnetic beads, this chemical probe allows for straightforward extraction of metabolites from human samples and release under mild conditions. This isolation from the sample matrix results in significantly reduced ion suppression, an increased mass spectrometric sensitivity, and facilitates the detection of metabolites in femtomole quantities. The chemoselective probe was applied to the analysis of human fecal samples, resulting in the discovery of four metabolites previously unreported in this sample type and confirmation of the presence of medically relevant gut microbiota-derived metabolites.

Conformational Change of Self-Assembled DNA Nanotubes Induced by Two-Photon Excitation

Two-photon-regulated, shape-changing DNA nanostructures are demonstrated by integrating a DNA nanotube with a two-photon photocleavable module that enables the opening of the cavities of tube, and becomes partially single-stranded in response to two-photo

Decoupling fluorescence and photochromism in bifunctional azo derivatives for bulk emissive structures

Bifunctional molecules that combine independent push-pull fluorophores and azo photochromes have been synthesized to create fluorescent structures upon light-induced migration in neat thin films. Their photochromic and emissive properties have been systematically investigated and interpreted in light of those of the corresponding model compounds. Fluorescence lifetimes and photoisomerization and fluorescence quantum yields have been determined in toluene solution. Kinetic analyses of the femtosecond transient absorption spectra reveal that the fluorophores evolve in a few picoseconds into a distorted intramolecular charge-transfer excited state, strongly stabilized in energy. Radiative relaxation to the ground state occurred competitively with the energy-transfer process to the azo moiety. Introduction of a 10 A-long rigid and nonconjugated bridge between the photoactive units efficiently inhibits the energy transfer while it imparts enhanced free volume, which favors photoactivated molecular migration in the solid state. Copyright

Tunable emissive thin films through ICT photodisruption of nitro-substituted triarylamines

UV-assisted photocleavage in the solid state of orange emitting nitro-substituted triarylamines leads to the appearance of blue emission following photodisruption of the ICT state.

PRODUCTS FROM NITRATION OF 3,5-SUBSTITUTED BENZOIC ACIDS

During the nitration of 3,5-substituted benzoic acids by a nitrating mixture one isomer is formed if one of the substituents is an acetylamino group.