883565-86-4

Basic information

• Product Name: 5α-17β-dihydroxy-11β-[4-(N-isopropyl-N-trimethylsilylamino)phenyl]-17α-ethynyl-3,3-(ethane-1,2-diyldioxy)-estra-9-ene
• Synonyms: 5α-17β-dihydroxy-11β-[4-(N-isopropyl-N-trimethylsilylamino)phenyl]-17α-ethynyl-3,3-(ethane-1,2-diyldioxy)-estra-9-ene
• CAS NO: 883565-86-4
• Molecular Weight: 505.698
• Mol File: 883565-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5α-17β-dihydroxy-11β-[4-(N-isopropyl-N-trimethylsilylamino)phenyl]-17α-ethynyl-3,3-(ethane-1,2-diyldioxy)-estra-9-ene(CAS DataBase Reference)
• NIST Chemistry Reference: 5α-17β-dihydroxy-11β-[4-(N-isopropyl-N-trimethylsilylamino)phenyl]-17α-ethynyl-3,3-(ethane-1,2-diyldioxy)-estra-9-ene(883565-86-4)
• EPA Substance Registry System: 5α-17β-dihydroxy-11β-[4-(N-isopropyl-N-trimethylsilylamino)phenyl]-17α-ethynyl-3,3-(ethane-1,2-diyldioxy)-estra-9-ene(883565-86-4)

Safety Data

• Hazardous Substances Data: 883565-86-4(Hazardous Substances Data)

Upstream product

• 121086-19-9 (4-bromophenyl)isopropylamine 
• 883565-85-3 4-(N-isopropyl-N-trimethylsilylamino)phenyl bromide 
• 84371-57-3 (5'R,8'S,10'R,13'S,14'S,17'S)-13'-methyl-17'-(prop-1-yn-1-yl)-1',2',7',8',12',13',14',15',16',17'-decahydro-4'H,6'H-spiro[[1,3]dioxolane-2,3'-[5,10]epoxycyclopenta[a]phenanthren]-17'-ol 

Downstream Products

• 883565-87-5 17β-hydroxy-11β-(4-([1-methylethyl]-aminophenyl))-17α-[prop-1-ynyl]estra-4,9-dien-3-one 

Relevant articles and documents

Synthesis and evaluation of [11C]RU40555, a selective glucocorticoid receptor antagonist

We demonstrated the synthesis of carbon-11 labeled 17-α-hydroxy-11- β-/4-/[methyl]-[1-methylethyl]-aminophenyl/-17α-[prop-1-ynyl] esta-4-9-diene-3-one (RU40555), a selective glucocorticoid receptor (GR) antagonist, and examined the in vivo profile of [su