88374-33-8Relevant academic research and scientific papers
Design, synthesis and biological evaluation of new 5-nitro benzimidazole derivatives as AT1 antagonists with anti-hypertension activities
Zhu, Weibo,Da, Yajing,Wu, Dan,Zheng, Huiling,Zhu, Linfeng,Wang, Li,Yan, Yijia,Chen, Zhilong
, p. 2294 - 2302 (2014/04/17)
The design, synthesis, in vitro and in vivo evaluation of 5-nitro benzimidazole with 1,4-disubsituted or 1,5-disubsituted indole derivatives as novel angiotensin II receptor antagonist is outlined. Radioligand binding assays showed that 2-(4-((2-butyl-5-n
Benzotriazole-assisted thioacylation
Katritzky, Alan R.,Witek, Rachel M.,Rodriguez-Garcia, Valerie,Mohapatra, Prabhu P.,Rogers, James W.,Cusido, Janet,Abdel-Fattah, Ashraf A. A.,Steel, Peter J.
, p. 7866 - 7881 (2007/10/03)
Benzotriazole reagents for thioacylation (RCSBt), thiocarbamoylation (RR'NCSBt), aryl/alkoxy-thioacylation (ROCSBt), and aryl/alkylthiothioacylation (RSCSBt) are synthesized, and their utility is assessed by syntheses of representative heteroaryl thioureas 3a-g, thioamides 15a-s, thionoesters 16a-h, thiocarbamates 17a-e, dithiocarbamates 18a-d, thiocarbonates 19a-c, and dithiocarbonates 20a-c.
