88382-05-2Relevant academic research and scientific papers
Arylboronic Acid-Catalyzed C-Allylation of Unprotected Oximes: Total Synthesis of N-Me-Euphococcine
Kürti, László,Kattamuri, Padmanabha V.,Siitonen, Juha H.,Yousufuddin, Muhammed
, (2020/03/24)
O-Unprotected keto-and aldoximes are readily C-allylated with allyl diisopropyl boronate in the presence of arylboronic acid catalysts to yield highly substituted N-α-secondary and tertiary homoallylic hydroxylamines. The method was used in the total synthesis of the trace alkaloid N-Me-Euphococcine.
Exploring nitrone chemistry: Towards the enantiodivergent synthesis of 6-substituted 4-hydroxypipecolic acid derivatives
Merino, Pedro,Mannucci, Vanni,Tejero, Tomas
experimental part, p. 3943 - 3959 (2009/04/08)
A methodology for the stereoselective preparation of all-cis 6-substituted 4-hydroxypipecolic acid derivatives using nitrone chemistry, involving both nucleophilic additions and cycloadditions, is presented. The N-benzyl nitrone derived from 1,2-di-O-isop
Addition of Allylboronates to Schiff Bases and to Oximes
Hoffmann, Reinhard W.,Eichler, Guenter,Endesfelder, Andreas
, p. 2000 - 2007 (2007/10/02)
Clean addition of allylboronates of Type 3 to Schiff bases 2 leads to the secondary homoallylamines 4.Analogous addition to the oximes 9 results in the formation of the hydroxylamines 13.The latter allow the generation of the primary homoallylamines 14.
