883973-92-0Relevant articles and documents
A novel series of urea-based peptidomimetic calpain inhibitors
Sanders, M. Lee,Donkor, Isaac O.
, p. 1965 - 1968 (2007/10/03)
A series of peptide aldehyde derivatives in which the P2 chiral carbon has been replaced with nitrogen were synthesized as urea-based peptidomimetic inhibitors of μ-calpain. The compounds mirrored the general SAR of peptidyl aldehyde calpain inhibitors but displayed greater selectivity for μ-calpain over cathepsin B.