883984-95-0

Basic information

• Product Name: Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate
• Synonyms: Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate;Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carbox
• CAS NO: 883984-95-0
• Molecular Formula: C₁₉H₁₈ClN₃O₄
• Molecular Weight: 387.81692
• Mol File: 883984-95-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate(883984-95-0)
• EPA Substance Registry System: Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate(883984-95-0)

Safety Data

• Hazardous Substances Data: 883984-95-0(Hazardous Substances Data)

Usage

General Description

Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate is a complex chemical compound with a long and specific name. It is a spiro compound containing a piperidine ring and a pyridooxazine ring. The benzyl group is attached to the piperidine ring, and the molecule also contains a carboxylate functional group. The presence of a chlorine atom and a ketone group in the structure adds to its complexity. Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate may have potential applications in pharmaceuticals or materials science due to its intricate and unique structure.

Upstream product

• 45644-21-1 6-chloropyridin-2-amine 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 159603-71-1 t-butyl N-(6-chloro-2-pyridinyl)carbamate 

Downstream Products

• 885031-90-3 benzyl 7'-chloro-1'-(methoxymethyl)-2'-oxo-1',2'-dihydro-1H-spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate 
• 885031-88-9 benzyl 7'-chloro-1'-methyl-2'-oxo-1',2'-dihydro-1H-spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate 
• 753440-87-8 spiro[piperidine-4,4’-[4H]pyrido[2,3-d][1,3]oxazin]-2'(1‘H)-one 

Relevant articles and documents

NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS

The invention relates to novel heterocyclic compounds of general formula (I), as well as their pharmaceutically acceptable salts, and their enantiomers. The invention also relates to the use thereof as a medicinal product, preferably in the prevention and/or treatment of inflammatory diseases with a neurogenic component or use thereof as a cosmetic. The compounds of the present invention act as antagonists of the CGRP-R receptor.

NOVEL COMPOUNDS

The present invention relates to new CGRP-antagonists of general formula I wherein U, V, X, Y, R1, R2, R3 and R4 are defined as in the description, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates, the mixtures thereof and the salts thereof and the hydrates of the salts, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, their use and processes for preparing them.

Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: Development of novel spiropiperidines

Several novel spiropiperidine-based CGRP receptor antagonists have been developed that maintain good potency and have reduced potential for metabolism.