883986-23-0Relevant articles and documents
Discovery of AZD2932, a new Quinazoline Ether Inhibitor with high affinity for VEGFR-2 and PDGFR tyrosine kinases
Plé, Patrick A.,Jung, Frédéric,Ashton, Sue,Hennequin, Laurent,Laine, Romuald,Morgentin, Rémy,Pasquet, Georges,Taylor, Sian
, p. 262 - 266 (2012/02/16)
A new series of Quinazoline Ether Inhibitor which potently inhibits VEGFR-2 and PDGFR tyrosine kinases is described here. In vitro, pharmacokinetics and in vivo evaluations led to the selection of AZD2932.