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2-Propenoic acid, 3-[2-(difluoromethoxy)phenyl]-, also known as 3-(2-Difluoromethoxyphenyl)acrylic acid, is an organic compound characterized by its molecular formula C9H8F2O3. This chemical features a difluoromethoxy group attached to a phenyl ring, which is in turn connected to a 3-position acrylic acid moiety. It is a colorless to pale yellow liquid with a molecular weight of 206.16 g/mol. 2-Propenoic acid, 3-[2-(difluoromethoxy)phenyl]- is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the production of certain herbicides and insecticides. Due to its reactivity and functional groups, it is also of interest in the field of materials science for the development of new polymers and other specialty chemicals.

884-05-9

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884-05-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 884-05-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,8 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 884-05:
(5*8)+(4*8)+(3*4)+(2*0)+(1*5)=89
89 % 10 = 9
So 884-05-9 is a valid CAS Registry Number.

884-05-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2E)-3-[2-(Difluoromethoxy)phenyl]acrylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:884-05-9 SDS

884-05-9Downstream Products

884-05-9Relevant academic research and scientific papers

New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation

Angeli, Andrea,Arifuddin, Mohammed,Singh, Priti,Supuran, Claudiu T.,Swain, Baijayantimala

, (2020/07/03)

Two novel series of phenylacrylamide linked coumarins and sulfocoumarins (6a-p, 8a-i, and 14a-g) were synthesized and evaluated against four physiologically relevant human carbonic anhydrases (hCAs, EC 4.2.1.1), isoforms hCA I, hCA II, hCA IX and hCA XII for their inhibitory action. All new compounds when screened for carbonic anhydrase inhibitory activity have shown selective inhibition towards the tumor associated isoforms hCA IX and XII over CA I and II, with inhibition constants in the submicromolar to low nanomolar range. Compound 6b and 14g exhibited significant inhibition with low nanomolar potency against hCA IX, whereas 6k was effective against hCA XII. Compounds 6b, 14g and 6k may be considered as lead molecules for future development of cancer therapeutics based on a novel mechanism of action.

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