884-06-0

Basic information

• Product Name: 1-(3,4-DiMethoxyphenyl)-2-butanone
• Synonyms: 1-(3,4-DiMethoxyphenyl)-2-butanone;NSC 78466;Veratrylpropan-1-one;1-(3,4-Dimethoxyphenyl)butan-2-one
• CAS NO: 884-06-0
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208
• Product Categories: Aromatics;Miscellaneous Reagents
• Mol File: 884-06-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 298.4 °C at 760 mmHg
• Flash Point: 125.1 °C
• Appearance: /
• Density: 1.039 g/cm³
• Vapor Pressure: 0.00127mmHg at 25°C
• Refractive Index: 1.495
• Storage Temp.: 2-8°C
• Solubility: Acetone, Chloroform, Dichloromethane, Methanol
• CAS DataBase Reference: 1-(3,4-DiMethoxyphenyl)-2-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-DiMethoxyphenyl)-2-butanone(884-06-0)
• EPA Substance Registry System: 1-(3,4-DiMethoxyphenyl)-2-butanone(884-06-0)

Safety Data

• Hazardous Substances Data: 884-06-0(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Oil

Uses

1-(3,4-Dimethoxyphenyl)-2-butanone (cas# 884-06-0) is a compound useful in organic synthesis.

InChI:InChI=1/C12H16O3/c1-4-10(13)7-9-5-6-11(14-2)12(8-9)15-3/h5-6,8H,4,7H2,1-3H3

Upstream product

• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 100613-28-3 methyl 4-(3,4-dimethoxyphenyl)-3-oxobutanoate 
• 925-90-6 ethylmagnesium bromide 
• 155955-78-5 3,4-dimethoxyphenylacetic acid N,O-dimethylhydroxyamide 
• 78765-14-7 t-butyl 2-ethyl-2,3-epoxy-3-(3',4'-dimethoxyphenyl)-propanoate 

Downstream Products

• 78765-15-8 4-(3',4'-dimethoxyphenyl)-3-hexnone 
• 17249-61-5 (5,6-dimethoxybenzofuran-2-yl)ethan-2-one 
• 468-91-7 4-(3,4-dimethoxy-phenyl)-3-(4-fluoro-phenyl)-hexan-3-ol 
• 110249-50-8 4-(3,4-dimethoxy-phenyl)-3-phenyl-hexan-3-ol 
• 482-57-5 (+/-)-erythro-3-(3,4-dimethoxy-phenyl)-4-(4-fluoro-phenyl)-hexane 
• 439-39-4 4-[(1RS,2SR)-1-ethyl-2-(4-fluoro-phenyl)-butyl]-pyrocatechol 
• 112744-08-8 (+/-)-erythro-3-(3,4-dimethoxy-phenyl)-4-phenyl-hexane 
• 5459-28-9 4-((1RS,2SR)-1-ethyl-2-phenyl-butyl)-pyrocatechol 
• 78765-18-1 C₂₁H₂₆O₃ 
• 71113-07-0 3'-hydroxydiethylstilbestrol 
• 78765-16-9 3-(p-methoxyphenyl)-4-(3',4'-dimethoxyphenyl)-3-hexanol 
• 84675-75-2 3-(p-methoxyphenyl)-4-(3',4'-dimethoxyphenyl)-3-hexene 
• 321394-48-3 4-ethyl-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 
• 321394-42-7 2-[1-(3,4-dimethoxy-benzyl)-propylamino]-1-phenyl-ethanol 

Relevant articles and documents

Synthesis of Benzo[ b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogues, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Two general routes to 1,4-disubstituted-2,3,4,5-tetrahydro- 1H-3-benzazepines.

[structure] Two general routes to 1,4-disubstituted-2,3,4, 5-tetrahydro-1H-3-benzazepines are described. Both routes utilize an appropriately functionalized phenethylamino alcohol as the penultimate intermediate: the first route makes use of the reductive amination of a benzyl alkyl ketone with alpha-(aminomethyl)benzyl alcohol, while the second route utilizes the addition of a Grignard reagent to the oxazolidine derived from a substitued phenylacetaldehyde and alpha-(methylaminomethyl)benzyl alcohol. In all cases studied, the cis-1,4-disubstituted-2,3,4, 5-tetrahydro-1H-3-benzazepine was obtained as the major product.