88404-95-9Relevant academic research and scientific papers
Reactivity of 2-Methylene-1,3-dicarbonyl Compounds. Syntheses of 2,2,3-Trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones
Yamauchi, Masashige,Katayama, Sadamu,Watanabe, Toshio
, p. 2887 - 2891 (2007/10/02)
Michael condensation of 2-methylsulfinylmethyl-1,3-dicarbonyl compounds (3) or 2-methylene-1,3-dicarbonyl compounds (4) with 4-hydroxycoumarin (5) at ambient temperature gave 2--1,3-dicarbonyl compounds (6).Treatment of 6 with methanolic hydrogen chloride resulted in the regioselective formation of 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones.Keywords - 2-methylene-1,3-dicarbonyl compound; 2-methylsulfinylmethyl-1,3-dicarbonyl compound; 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-one; regioselective cyclization; Michael condensation
