88404-97-1

Upstream product

• 67-56-1 methanol 
• 88404-95-9 2-(4-Hydroxy-2-oxo-2H-chromen-3-ylmethyl)-1-phenyl-butane-1,3-dione 
• 37559-20-9 1-phenyl-2-methylenebutane-1,3-dione 
• 85054-04-2 2-Methanesulfinylmethyl-1-phenyl-butane-1,3-dione 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 

Relevant academic research and scientific papers

Reactivity of 2-Methylene-1,3-dicarbonyl Compounds. Syntheses of 2,2,3-Trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones

Michael condensation of 2-methylsulfinylmethyl-1,3-dicarbonyl compounds (3) or 2-methylene-1,3-dicarbonyl compounds (4) with 4-hydroxycoumarin (5) at ambient temperature gave 2--1,3-dicarbonyl compounds (6).Treatment of 6 with methanolic hydrogen chloride resulted in the regioselective formation of 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-ones.Keywords - 2-methylene-1,3-dicarbonyl compound; 2-methylsulfinylmethyl-1,3-dicarbonyl compound; 2,2,3-trisubstituted-3,4-dihydro-2H-pyranobenzopyran-5-one; regioselective cyclization; Michael condensation