884069-49-2Relevant academic research and scientific papers
Copper-catalyzed tandem C-N bond formation reaction: Selective synthesis of 2-(trifluoromethyl)benzimidazoles
Chen, Mu-Wang,Zhang, Xing-Guo,Zhong, Ping,Hu, Mao-Lin
experimental part, p. 1431 - 1436 (2009/12/08)
A highly practical method for the synthesis of fluorinated benzimidazoles was developed by CuI/TMEDA-catalyzed cross-coupling reaction of N-(2-haloaryl)trifluoroacetimidoyl chlorides with primary amines. The present double amination process tolerates the
Synthesis of 2-fluoroalkylbenzimidazoles via copper(i)-catalyzed tandem reactions
Zhu, Jiangtao,Xie, Haibo,Chen, Zixian,Li, Shan,Wu, Yongming
supporting information; experimental part, p. 2338 - 2340 (2009/09/06)
Preparation of 2-fluoroalkylbenzimidazoles from N-aryl trifluoroacetimidoyl (or bromodifluoroacetimidoyl) chlorides and primary amines has been achieved via copper(i)-catalyzed tandem reactions. The Royal Society of Chemistry 2009.
