88418-55-7Relevant academic research and scientific papers
1-AROYL-2-BENZYL-5-HYDROXYPYRAZOLIDINES
Sviridova, L. A.,Afanas'eva, S. V.,Golubeva, G. A.,Torocheshnikov, V. N.,Terent'ev, P. B.,et al.
, p. 1001 - 1004 (2007/10/02)
The PMR spectral data show that 1-aroyl-2-benzyl-5-hydroxypyrazolidines are preferentially present in cyclic form in solution, while the proportion of the linear from increases to ca. 50percent in the gaseous phase, according to mass spectra.
SYNTHESIS OF 5-HYDROXY- AND 5-ACYLHYDRAZINOPYRAZOLIDINES BY THE REACTION OF &β-SUBSTITUTED HYDRAZIDES WITH &α,&β-UNSATURATED ALDEHYDES AND THEIR BIOLOGICAL ACTIVITY
Zelenin, K. N.,Dovgilevich, A. V.,Bezhan, I. P.,Golubeva, G. A.,Sviridova, L. A.,et al.
, p. 529 - 536 (2007/10/02)
The reaction of β-substituted hydrazides with alkenals (acrolein, methacrolein, crotonaldehyde, and cinnamaldehyde) serves as a method for the synthesis of the corresponding 1-acyl-5-hydroxypyrazolidines and, in a number of cases, 1-acyl-5-acylhydrazinopyrazolidines.Some of the 1-acyl-5-hydroxypyrazolidines obtained have antiphlogistic activity.
