88422-19-9

Usage

Uses

Used in Organic Chemistry:
(S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE& is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new pharmaceuticals and organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE& is employed as a chiral auxiliary in asymmetric synthesis. Its specific stereochemical properties are valuable for the production of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and minimizing potential side effects of drugs.
Used in Asymmetric Synthesis:
As a chiral auxiliary, (S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE& plays a significant role in asymmetric synthesis, aiding in the creation of molecules with specific three-dimensional configurations that are essential for biological activity.
Used as a Ligand in Asymmetric Catalysis:
(S)-(-)-1-(4-NITROPHENYL)-2-PYRROLIDINE& also serves as a ligand for asymmetric catalysis, enhancing the selectivity of catalytic reactions and improving the yield of desired enantiomerically pure products.

InChI:InChI=1/C11H14N2O3/c14-8-11-2-1-7-12(11)9-3-5-10(6-4-9)13(15)16/h3-6,11,14H,1-2,7-8H2/t11-/m0/s1

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 66158-68-7 (S)-1-(2-(hydroxymethyl) pyrrolidin-1-yl)ethanone 
• 586-78-7 para-nitrophenyl bromide 
• 509151-88-6 1-[(S)-2-(4-Nitro-phenoxymethyl)-pyrrolidin-1-yl]-ethanone 

Downstream Products

• 132041-37-3 [(S)-1-(4-Amino-phenyl)-pyrrolidin-2-yl]-methanol 

Relevant academic research and scientific papers

Chirality and hydrogen bonding in molecular crystals for phase-matched second-harmonic generation: N-(4-nitrophenyl)-(L)-prolinol (NPP)

The higher second-harmonic efficiency, in powder, of a new organic molecular crystal N (4-nitrophenyl)-(L)-prolinol (NPP) is reported.Electronic polarizability of NPP molecules relates to that of other para-nitroaniline-like structures such as that of pre

ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS

Provided herein are compounds having a structure selected from among Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V) and Formula (VI) that are androgen receptor modulators and/or androgen receptor binding agents. Also disclosed are met

Synthesis and second-order nonlinearities of chiral prolinol-substituted chromophores

A new series of thiophene- and furan-containing chromophores with a chiral prolinol donor and a sulfone acceptor has been synthesized. The UV-vis absorptions, second-order nonlinear optical properties, and X-ray crystal structures are described.

Thermodynamics of binding between α- and β-cyclodextrins and some p-nitro-aniline derivatives: Reconsidering the enthalpy-entropy compensation effect

The thermodynamics of binding between native α- and β-cyclodextrin towards several p-nitro-aniline derivatives was examined, in order to gain further insights about the occurrence of different interaction modes for the two hosts. Valuable information was

Observation of O→N type smiles rearrangement in certain alkyl aryl nitro compounds

Smiles rearrangements on some alkyl aryl nitro compounds having NH2 group as the nucleophile and oxygen as the leaving group are reported.