88431-07-6Relevant academic research and scientific papers
Pd-catalyzed allylic alkylation of thioamides
Rong, Bin,Ding, Lei,Yu, Hailei,Yang, Qin,Liu, Xuliang,Xu, Dongfang,Li, Guisheng,Zhao, Baoguo
, p. 6501 - 6503 (2013)
This work describes the first Pd-catalyzed allylic alkylation of thioamides. Various thioamides were efficiently α-allylated in high yields and with excellent selectivity for monoallylation under mild reaction conditions. The process not only provides a facile method for the synthesis of functionalized thioamides, but also presents a useful transformation for synthetically important thioamides.
1,3-Asymmetric Induction: Highly Stereoselective Synthesis of 2,4-Trans-Disubstituted γ-Butyrolactones and γ-Butyrothiolactones
Tamaru, Yoshinao,Mizutani, Masato,Furukawa, Yutaka,Kawamura, Shin-ichi,Yoshida, Zen-ichi,et al.
, p. 1079 - 1085 (2007/10/02)
A novel 1,3-trans asymmetric induction has been observed for the halolactonization of α- and α,β-substituted γ,δ-unsaturated amides.The 1,3-trans selectivity is lost in the threo diastereomers of amides with β-OH or β-OAc substituent, due to the 1,2-cis d
