884494-34-2

Basic information

• Product Name: 2-ETHYNYL-5-FLUOROPYRIDINE
• Synonyms: 2-ETHYNYL-5-FLUOROPYRIDINE
• CAS NO: 884494-34-2
• Molecular Formula: C₇H₄FN
• Molecular Weight: 121.11
• Product Categories: Fluorine series
• Mol File: 884494-34-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 150.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.16±0.22(Predicted)
• CAS DataBase Reference: 2-ETHYNYL-5-FLUOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYNYL-5-FLUOROPYRIDINE(884494-34-2)
• EPA Substance Registry System: 2-ETHYNYL-5-FLUOROPYRIDINE(884494-34-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 884494-34-2(Hazardous Substances Data)

Usage

General Description

2-Ethynyl-5-fluoropyridine is a chemical compound with the molecular formula C7H4FN. It is a pyridine derivative with a fluorine atom at the 5-position and an ethynyl group at the 2-position of the pyridine ring. 2-ETHYNYL-5-FLUOROPYRIDINE is a member of the pyridine family, which is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and properties make it a valuable building block for the synthesis of various compounds, including pharmaceutical intermediates and heterocyclic compounds. It is also used in organic synthesis as a reagent and as a starting material for the preparation of bioactive molecules. Overall, 2-ethynyl-5-fluoropyridine is an important chemical compound with versatile applications in the field of organic chemistry.

Upstream product

• 884494-40-0 2-(5-fluoro-2-pyridyl)ethynyl-trimethylsilane 
• 159870-80-1 5-fluoro-2-iodopyridine 
• 41404-58-4 2-bromo-5-fluoropyridine 
• 31181-88-1 5-fluoropicolinaldehyde 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 904694-30-0 dimethylhydroxymethyl-5-fluoro-2-pyridylacetylene 

Downstream Products

• 1410040-87-7 N-{2-[5-(5-fluoropyridin-2-yl)-1,2-oxazol-3-yl]ethyl}-5-methyl-2-(2H-1,2,3-triazol-2-yl)benzamide 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

Efficient synthesis of 2-pyridylenynes and application in cobalt-catalysed benzannulation reactions

The cobalt-catalysed benzannulation of 2-pyridine-substituted enynes gave 2,3-bis(2-pyridyl)styrenes in moderate yields. The reaction with dibromomethane as well as diiodomethane generated the corresponding planar-chiral bispyridinium salts in good yields

TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.