884512-27-0

Upstream product

• 630-17-1 2,2-dimethylpropyl bromide 
• 163438-09-3 (R)-1-Boc-nipecotic acid 
• 634590-61-7 (4-methoxybutyl)magnesium chloride 
• 884512-28-1 2-((S)-1-hydroxy-5-methoxy-1-((R)-N-Boc-piperidin-3-yl)pentyl)[tert-butyldimethylsiloxy]benzene 
• 884510-86-5 (R)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 

Downstream Products

• 952709-02-3 ((1S,3R,4S)-3-(tert-butoxycarbonylamino)-4-hydroxycyclopentyl)((R)-3-((S)-1-hydroxy-5-methoxy-1-(2-(2,2-(dimethyl)propoxy)phenyl)pentyl)piperidin-1-yl)methanone 

Relevant academic research and scientific papers

RENIN INHIBITORS

Disclosed are compounds according to Formula (I): wherein the variables are defined herein. Such compounds are can bind aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic pro

PIPERIDINE AND MORPHOLINE RENIN INHIBITORS

Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.