884652-89-5

Basic information

• Product Name: N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide
• Synonyms: N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide
• CAS NO: 884652-89-5
• Molecular Weight: 570.695
• Mol File: 884652-89-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide(884652-89-5)
• EPA Substance Registry System: N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide(884652-89-5)

Safety Data

• Hazardous Substances Data: 884652-89-5(Hazardous Substances Data)

Upstream product

• 955969-22-9 {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylamino-cyclopentyl)-6-(2,2-diphenyl-ethylamino)-9H-purin-2-yl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester trifluoroacetate 
• 5451-40-1 2,6-dichloro-7H-purine 
• 955969-21-8 {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylamino-cyclopentyl)-6-(2,2-diphenyl-ethylamino)-9H-purin-2-yl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester 
• 60410-16-4 (1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate 
• 884654-01-7 (1S,2R,3S,5R)-3-(bis-(tert-butyloxycarbonyl))-amino-5-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-cyclopentane-1,2-diol 
• 955114-75-7 (1 S,2R,3S,5R)-3-Amino-5-(2,6-dichloro-purin-9-yl)-cyclopentane-1,2-diol trifluoroacetate 
• 884654-00-6 {2-chloro-9-[(1R,4S)-4-(di-boc-amino)-cyclopent-2-enyl]-9H-purin-6-yl}-(2,2-diphenyl-ethyl)-amine 
• 884653-97-8 (1S,2R,3S,5R)-(di-tert-butoxycarbonylamino)-5-(2,6-dichloro-purin-9-yl)-cyclopentane-1,2-diol 
• 884653-96-7 di-boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine 
• 884653-99-0 N-[(1S,2R,3S,4R)-4-(2,6-dichloro-purin-9-yl)-2.3-dihydroxy-cyclopentyl]-propionamide 
• 884653-95-6 carbonic acid (1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl ester ethyl ester 
• 884652-29-3 N-{(1S,2 R,3S,4R)-4-[2-Chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide 

Downstream Products

• 955967-52-9 N-((1S,2R,3S,4R)-4-{6-(2,2-diphenylethylamino)-2-[(R)-3-(3-pyridin-2-ylmethylureido)-pyrrolidin-1-yl]-purin-9-yl}-2,3-dihydroxycyclopentyl)propionamide trifluoroacetate 
• 955967-88-1 N-((1S,2R,3S,4R)-4-{6-(2,2-diphenylethylamino)-2-[(R)-3-(3-pyridin-3-ylmethylureido)-pyrrolidin-1-yl]-purin-9-yl}-2,3-dihydroxycyclopentyl)propionamide trifluoroacetate 
• 955969-91-2 N-{(1S,2R,3S,4R)-4-[2-[(R)-3-(2-acetylamino-4-methyl-thiazole-5-sulfonylamino)-pyrrolidin-1-yl]-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide trifluoroacetate 
• 955967-49-4 N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate 
• 955968-27-1 N-[(1S,2R,3S,4R)-4-(6-(2,2-diphenylethylamino)-2-{(R)-3-[3-(4-phenoxyphenyl)ureido]pyrrolidin-1-yl}purin-9-yl)-2,3-dihydroxycyclopentyl]propionamide trifluoroacetate 
• 955967-94-9 N-{(1S,2R,3S,4R)-4-[2-[(R)-3-(4-acetylaminobenzenesulfonylamino)pyrrolidin-1-yl]-6-(2,2-diphenylethylamino)purin-9-yl]-2,3-dihydroxycyclopentyl}propionamide trifluoroacetate 
• 955967-96-1 N-{(1S,2R,3S,4R)-4-[2-[(R)-3-(4,5-dihydro-1H-imidazol-2-ylamino)pyrrolidin-1-yl]-6-(2,2-diphenylethylamino)purin-9-yl]-2,3-dihydroxycyclopentyl}propionamide 
• 1011483-38-7 [(1S,2R,3S,4R)-4-(2-chloro-6{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylamino-cyclopentyl)-6-(2,2-diphenyl-ethylamino)-9H-purin-2-yl]-pyrrolidin-3-ylamino}-purin-9-yl)-2,3-dihydroxy-cyclopentyl]-di-carbamic acid tert-butyl ester 

Relevant articles and documents

Organic Compounds

A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein R1, R2 and R3 are as defined herein.

ORGANIC COMPOUNDS

A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals wherein Rl, R2 and R3 are as defined herein.

PURINE DERIVATIVES FOR USE AS ADENOSIN A-2A RECEPTOR AGONISTS

Compounds of formula (I) in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adenosine A2A receptor,