884660-47-3

Basic information

• Product Name: 6-fluoro-5-iodopyridin-2-aMine
• Synonyms: 6-fluoro-5-iodopyridin-2-aMine;6-amino-2-fluoro-3-iodopyridine
• CAS NO: 884660-47-3
• Molecular Formula: C₅H₄FIN₂
• Molecular Weight: 238.0015332
• Mol File: 884660-47-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 125 °C
• Boiling Point: 310.7±42.0 °C(Predicted)
• Appearance: /
• Density: 2.139±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.16±0.10(Predicted)
• CAS DataBase Reference: 6-fluoro-5-iodopyridin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-fluoro-5-iodopyridin-2-aMine(884660-47-3)
• EPA Substance Registry System: 6-fluoro-5-iodopyridin-2-aMine(884660-47-3)

Safety Data

• Hazardous Substances Data: 884660-47-3(Hazardous Substances Data)

Usage

General Description

6-fluoro-5-iodopyridin-2-amine is a chemical compound with the molecular formula C5H4FIN. It is a derivative of pyridine and contains both fluorine and iodine atoms along with an amino group. 6-fluoro-5-iodopyridin-2-aMine is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceuticals and agrochemicals. It can also be used as a reagent in organic chemistry reactions to introduce the fluorine and iodine atoms into different organic molecules. The unique combination of fluorine and iodine in this compound makes it an important starting material for the preparation of various functionalized pyridine derivatives, which have potential applications in drug discovery and development.

Upstream product

• 1597-32-6 6-fluoro-pyridin-2-ylamine 
• 884660-46-2 N-(6-fluoro-5-iodopyridin-2-yl)acetamide 
• 141-86-6 2.6-diaminopyridine 
• 884660-45-1 N-(6-amino-5-iodopyridin-2-yl)acetamide 
• 856851-34-8 2,6-diamino-3-iodopyridine 

Downstream Products

• 884660-49-5 6-(2-(4-nitrophenyl)ethoxy)-2-fluoro-3-iodopyridine 
• 884660-53-1 6-[2-(4-nitrophenyl)ethoxy]-3-(β-D-glycero-pentofuran-3'-ulos-1'-yl)-2-fluoropyridine 
• 884660-56-4 3-[2-deoxy-β-D-erythro-pentafuranosyl]-2-fluoro-6-[2-(4-nitrophenyl)ethoxy]pyridine 
• 884660-48-4 2-fluoro-6-hydroxy-3-iodopyridine 

Relevant articles and documents

NOVEL CRYSTAL OF (3S)-3-[2-(6-AMINO-2-FLUOROPYRIDINE-3-YL)-4-FLUORO-1H-IMIDAZOLE-5-YL]-7-[5-CHLORO-2-(1H-TETRAZOLE-1-YL)PHENYL]-2,3-DIHYDROINDOLIZINE-5(1H)-ONE

Provided is a novel crystal form of (3S)-3-[2-(6-amino-2-fluoropyridin-3-yl)-4-fluoro-1H-imidazol-5-yl]-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-2,3-dihydroindolizin-5(1H)-one. Provided is (3S)-3-[2-(6-amino-2-fluoropyridin-3-yl)-4-fluoro-1H-imidazol-5-yl]-7-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-2,3-dihydroindolizin-5(1H)-one-3-hydroxybenzoic acid (1/1).

HETEROARYL COMPOUNDS AND USES THEREOF

Described herein are compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, isotopically labeled derivatives and radiolabeled derivative thereof, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for detecting and imaging Tau aggregates in the brain for detection of Alzheimer's disease (AD) in a subject.

Syntheses of pyridine C-nucleosides as analogues of the natural nucleosides dC and dU

The syntheses of four pyrimidine C-nucleosides are described. These derivatives are designed as mimics of dC and dU, and in that respect, each can form two hydrogen bonds with complementary dG or dA residues. The minor groove O2 carbonyl in each derivativ