88481-71-4

Upstream product

• 88481-70-3 (2S,3R)-3-Benzyl-2-(1-methoxy-1-methylethoxy)-1,4-butandiol 
• 88481-72-5 (4S,5S)-5-Benzyl-4-hydroxymethyl-2-phenyl-1,3-dioxan 
• 172275-56-8 dibenzyl (2S,3R)-2-benzyl-3-hydroxybutanedioate 
• 88481-69-0 (2S,3R)-3-Benzyl-2-(1-methoxy-1-methylethoxy)bernsteinsaeure-diethylester 
• 73828-17-8 (2S,3R)-3-Benzyl-2-hydroxybernsteinsaeure-diethylester 

Downstream Products

• 88481-74-7 (2S,3S)-2-Benzyl-3-benzyloxy-butane-1,4-diol 
• 88481-73-6 (2S,3S)-3-Benzyl-4-benzyloxy-1,2-butandiol 
• 88481-75-8 (R)-2-<(phenylmethoxy)methyl>-3-benzenepropanol 
• 88481-72-5 (4S,5S)-5-Benzyl-4-hydroxymethyl-2-phenyl-1,3-dioxan 

Relevant academic research and scientific papers

Stereospecific high-affinity TRPV1 antagonists: Chiral N-(2-benzyl-3- pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues

Previously, we reported the thiourea antagonists 2a and 2b as potent and high affinity TRPV1 antagonists. For further optimization of the lead compounds, a series of their amide and α-substituted amide surrogates were investigated and novel chiral N-(2-be

Enantiomerically Pure Building Blocks for Syntheses from Branched Malates

Isocitric acid lactone (13) and the chiral building blocks (2S,3R)-4-bromo-1,2-epoxy-3-methyl-butane (21), cis- and trans 2,3-epoxy-2-methylsuccinates (23, 24), and the singly protected (2R)-2-methyl-, -2-allyl- and -2-benzyl-1,3-propanediols (32a, b, c)