885-11-0

Basic information

• Product Name: 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one
• Synonyms: 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one;4-nitrosoantipyrine;1,2-Dihydro-1,5-dimethyl-4-nitroso-2-phenyl-3H-pyrazol-3-one;1,2-Dihydro-1,5-dimethyl-4-nitroso-2-phenyl-3H-pyrazole-3-one;1,5-dimethyl-4-nitroso-2-phenyl-pyrazol-3-one;1,5-dimethyl-4-nitroso-2-phenylpyrazol-3-one;Nitrosoantipyrine
• CAS NO: 885-11-0
• Molecular Formula: C₁₁H₁₁N₃O₂
• Molecular Weight: 217.22394
• EINECS: 212-941-6
• Product Categories: Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 885-11-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 306.5°C at 760 mmHg
• Flash Point: 139.2°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.000767mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one(885-11-0)
• EPA Substance Registry System: 2,3-dimethyl-4-nitroso-1-phenyl-3-pyrazolin-5-one(885-11-0)

Safety Data

• Hazardous Substances Data: 885-11-0(Hazardous Substances Data)

Usage

Uses

Nitrosoantipyrine is a derivative of antipyrine (A697500), an analgesic agent.

InChI:InChI=1/C11H11N3O2/c1-8-10(12-16)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,1-2H3

Upstream product

• 60-80-0 antipyrine 
• 10544-72-6 dinitrogen tetraoxide 

Downstream Products

• 102157-48-2 1,5-dimethyl-2-phenyl-4-(3-phenyl-propylamino)-1,2-dihydro-pyrazol-3-one 
• 58-15-1 aminopyrine 
• 34760-47-9 4-cyclohexylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 860527-20-4 1,5-dimethyl-4-phenethylamino-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 15166-10-6 4-Ethylaminoantipyrin 
• 101116-41-0 1,5-dimethyl-2-phenyl-4-propylamino-1,2-dihydro-pyrazol-3-one 
• 1055-31-8 1,5,5'-trimethyl-2,2'-diphenyl-1,2,2',4'-tetrahydro-4,4'-azanylylidene-bis-pyrazol-3-one 
• 3615-24-5 ramifenazone 
• 6386-15-8 4-Isonitroso-3-methyl-pyrazolon-(5) 
• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 
• 30672-29-8 1,5-dimethyl-4-nitro-2-phenyl-1H-pyrazole-3(2H)-one 
• 1759-26-8 (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-sulfamic acid 
• 51944-19-5 1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-ethyl-urea 
• 51944-24-2 1-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-ethyl-thiourea 

Relevant articles and documents

Synthesis and structural characterization of lanthanum(III) complexes of 4-nitrosoantipyrine

A new series of La(III) complexes of the ligand with the general formula [La(L)2(a)3] and [La2(L)4(aa)3], (a = nitrate (1), thiocyanate (2), acetate (3) and propionate (4) ions, aa = sulphate (5), thiosulphate (6), oxalate (7) and malonate (8) ions with the ligand 4-nitrosoantipyrine (L) were synthesized and characterized using various physico-chemical studies. The primary ligand L acts as a bidentate ligand utilizing the carbonyl group and the nitroso group for bonding. The nitrate, thiocyanate, acetate and propionate ions are monovalent unidentate ligands, whereas sulphate, thiosulphate, oxalate and malonate ions are divalent bidentate ligands in the complexes 1-8. Based on spectral data and magnetic susceptibility measurements, geometry of the lanthanum(III) complexes were also proposed.

COMPARATIVE MASS SPECTROMETRIC BEHAVIOR OF o-HYDROXYNITROSO DERIVATIVES OF THE QUINOLINE, ISOQUINOLINE, AND COUMARIN SERIES

Benzo-substituted ortho-hydroxynitrosoquinoline and isoquinoline are found in the gas phase predominantly as the hydroxyimino-ortho-quinoid tautomeric form and under electron bombardment they do not undergo a second order Beckmann rearrangement.Molecular ions of 4-hydroxy-3-nitrosocarbostyryls and coumarin have almost exclusively the structure of the corresponding 2,4-dioxo-3-hydroxyiminohetarene; they also do not undergo rearrangement and decompose predominantly by retrodiene cleavage.