885012-89-5Relevant articles and documents
Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position
Rudra, Sonali,Sangita, Fnu,Gujrati, Arti,Pandya, Manisha,Bhateja, Pragya,Mathur, Tarun,Singhal, Smita,Rattan, Ashok,Salman, Mohammed,Das, Biswajit
, p. 4778 - 4783 (2008/02/11)
Novel oxazolidinone derivatives of the lead compound RBx 8700, containing methylene oxygen- and methylene sulfur-linked substituents at the C5-position, were synthesized. Antibacterial screening of these compounds against a panel of resistant and susceptible Gram-positive and fastidious Gram-negative bacteria gave compounds 2 and 4 as new antibacterial agents.
OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS
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Page/Page column 43, (2010/11/08)
The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.