885012-90-8

Basic information

• Product Name: (5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• Synonyms: (5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• CAS NO: 885012-90-8
• Molecular Weight: 422.437
• Mol File: 885012-90-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one(885012-90-8)
• EPA Substance Registry System: (5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one(885012-90-8)

Safety Data

• Hazardous Substances Data: 885012-90-8(Hazardous Substances Data)

Upstream product

• 885013-17-2 tert-butyl 4-(4-{(5R)-5-[(acetyloxy)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)piperazine-1-carboxylate 
• 154590-62-2 (R)-tert-butyl-4-(2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenyl)piperazine-1-carboxylate 
• 885012-89-5 ((5R)-3-{3-fluoro-4-[4-(5-nitro-2-thienyl)piperazin-1-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl)methyl acetate 

Relevant articles and documents

Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position

Novel oxazolidinone derivatives of the lead compound RBx 8700, containing methylene oxygen- and methylene sulfur-linked substituents at the C5-position, were synthesized. Antibacterial screening of these compounds against a panel of resistant and susceptible Gram-positive and fastidious Gram-negative bacteria gave compounds 2 and 4 as new antibacterial agents.