88503-22-4

Upstream product

• 77-78-1 dimethyl sulfate 
• 105173-18-0 5,7-dihydroxy-8-nitro-2-phenyl-4H-chromen-4-one 
• 74-88-4 methyl iodide 
• 480-40-0 5,7-dihydroxy-2-phenyl-chromen-4-one 

Downstream Products

• 272774-05-7 5-hydroxy-6-isopropylamino-7-methoxy-2-phenyl-chromen-4-one 
• 272773-95-2 8-isopropylamino-5,7-dimethoxy-2-phenyl-chromen-4-one 
• 272774-09-1 6-allylamino-5-hydroxy-7-methoxy-2-phenyl-chromen-4-one 
• 272774-06-8 5-hydroxy-7-methoxy-2-phenyl-6-propylamino-chromen-4-one 
• 272774-07-9 5-hydroxy-6-isobutylamino-7-methoxy-2-phenyl-chromen-4-one 
• 272773-96-3 5,7-dimethoxy-2-phenyl-8-propylamino-chromen-4-one 
• 272773-99-6 8-allylamino-5,7-dimethoxy-2-phenyl-chromen-4-one 
• 272773-97-4 8-isobutylamino-5,7-dimethoxy-2-phenyl-chromen-4-one 
• 272774-08-0 5-hydroxy-7-methoxy-6-(3-methyl-butylamino)-2-phenyl-chromen-4-one 
• 272773-98-5 5,7-dimethoxy-8-(3-methyl-butylamino)-2-phenyl-chromen-4-one 
• 272773-89-4 N-(5,7-dimethoxy-4-oxo-2-phenyl-4H-chromen-8-yl)-2,4-dinitro-benzenesulfonamide 
• 272773-90-7 N-(5,7-dimethoxy-4-oxo-2-phenyl-4H-chromen-8-yl)-N-isopropyl-2,4-dinitro-benzenesulfonamide 
• 272773-91-8 N-(5,7-dimethoxy-4-oxo-2-phenyl-4H-chromen-8-yl)-2,4-dinitro-N-propyl-benzenesulfonamide 
• 272773-92-9 N-(5,7-dimethoxy-4-oxo-2-phenyl-4H-chromen-8-yl)-N-isobutyl-2,4-dinitro-benzenesulfonamide 

Relevant academic research and scientific papers

α-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as α-glucosidase inhibitors

The SAR studies suggested that the C-ring of baicalein (1) was not necessary for the activity, and validated the importance of 2,3,4- trihydroxybenzoyl structure of 1. Thus, a series of 2,3,4-trihydroxybenzoyl- containing flavonoid analogs were investigat

A convenient extension of the Wessely-Moser rearrangement for the synthesis of substituted alkylaminoflavones as neuroprotective agents in vitro

A series of 8-alkylamino-5,7-dihydroxyflavones was prepared from chrysine via a seven step sequence. The synthesis of their 6-alkylamino isomers could be subsequently accomplished through a convenient extension of the Wessely-Moser rearrangement. These compounds were found to be efficient neuroprotective agents in vitro. (C) 2000 Elsevier Science Ltd. All rights reserved.