885126-83-0

Upstream product

• 108-46-3 recorcinol 
• 90-33-5 7-hydroxy-4-methyl-chromen-2-one 
• 10009-70-8 R-(+)-2-bromopropionic acid 

Downstream Products

• 1533457-14-5 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2-fluorophenyl)methylphosphonate 
• 1533457-15-6 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(4-fluorophenyl)methylphosphonate 
• 1533457-16-7 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2-chlorophenyl)methylphosphonate 
• 1533457-17-8 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(3-chlorophenyl)methylphosphonate 
• 1533457-18-9 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(4-chlorophenyl)methylphosphonate 
• 1533457-20-3 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(3-bromophenyl)methylphosphonate 
• 1533457-21-4 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(4-bromophenyl)methylphosphonate 
• 1533457-22-5 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(3-methoxyphenyl)methylphosphonate 
• 1533457-23-6 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(4-methoxyphenyl)methylphosphonate 
• 1533457-26-9 diethyl 1-((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)-1-phenylethylphosphonate 
• 1533457-27-0 diethyl 1-((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)-1-phenylbutylphosphonate 
• 1533457-28-1 diethyl 1-((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)-1-phenylpropylphosphonate 
• 1533457-29-2 diethyl 1-((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)-1-(4-chlorophenyl)ethylphosphonate 
• 1533457-30-5 diethyl 1-((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)-1-(4-methoxyphenyl)ethylphosphonate 

Relevant academic research and scientific papers

Coumarin-containing aminophosphonates bridged with chiral side chain: Synthesis and influence of chirality on cytotoxicity and DNA binding

A series of novel coumarin-containing α-Aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g', (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2- bromophenyl)methylphosphonate) was

A new convenient route to enantiopure 2-coumarinyloxypropanals: Application to the synthesis of optically active geiparvarin analogues

A new convenient route to enantiopure 2-coumarinyloxypropanals is described: Rosenmund reduction of (R)- or (S)-2-coumarinyloxypropanoyl chlorides afforded in good yields the corresponding 2-coumarinyloxypropanals. Their subsequent aldolic condensation with 3(2H)-furanones, followed by dehydration, led to enantiopure geiparvarin analogues now being investigated as promising antitumoral compounds.