885217-68-5

Upstream product

• 885217-64-1 (3S,7R,10S)-1-aza-3-ethyl-10-isopropyl-3-methyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 100-39-0 benzyl bromide 
• 885217-62-9 (3R,7R,10S)-1-aza-3-ethyl-10-isopropyl-3-methyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 885217-56-1 2-(2-[1,3]dioxolan-2-yl-ethylsulfanyl)-N-(1-hydroxymethyl-2-methyl-propyl)-acetamide 
• 885217-58-3 (3S,7R,10S)-1-aza-3-ethyl-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 885217-59-4 (3S,7R,10S)-1-aza-10-isopropyl-3-methyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 885217-57-2 (7R,10S)-1-aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 885217-55-0 (2-[1,3]-dioxolan-2-yl-ethylsulfanyl)-acetic acid methyl ester 

Relevant academic research and scientific papers

A concise total synthesis of (R)-puraquinonic acid

Distant relative: The configuration of the quaternary stereocenter in puraquinonic acid (see scheme, right) is defined by groups far removed from the point of asymmetry. The use of a bicyclic thioglycolate lactam to set the quaternary stereocenter at an e

A practical chiral bicyclic thioglycolate lactam auxiliary for stereoselective quaternary carbon formation

Chiral bicyclic thioglycolate lactams may be prepared in three steps from inexpensive commercial materials. The resulting lactams may be alkylated three times, twice using basic enolization and once using reductive enolization, to form α-quaternary carbox