885217-73-2

Upstream product

• 885217-61-8 (3S,6S,9aR)-6-benzyl-3-isopropyltetrahydro-8H-oxazolo[3,2-d][1,4]thiazepin-5(6H)-one 
• 885217-56-1 2-(2-[1,3]dioxolan-2-yl-ethylsulfanyl)-N-(1-hydroxymethyl-2-methyl-propyl)-acetamide 
• 885217-57-2 (7R,10S)-1-aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 885217-55-0 (2-[1,3]-dioxolan-2-yl-ethylsulfanyl)-acetic acid methyl ester 
• 885217-66-3 (3R,7R,10S)-1-aza-3-benzyl-10-isopropyl-3-methyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone 
• 75-03-6 ethyl iodide 

Relevant academic research and scientific papers

A practical chiral bicyclic thioglycolate lactam auxiliary for stereoselective quaternary carbon formation

Chiral bicyclic thioglycolate lactams may be prepared in three steps from inexpensive commercial materials. The resulting lactams may be alkylated three times, twice using basic enolization and once using reductive enolization, to form α-quaternary carbox