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885272-84-4

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885272-84-4 Usage

Description

Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis a chemical compound with the molecular formula C14H9N3. It is a derivative of imidazo[1,2-a]pyridine, featuring a phenyl group attached to the nitrogen atom at position 2. Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis of interest to researchers in medicinal chemistry and drug discovery due to its potential biological activity and structural features, which may contribute to the development of new pharmaceutical agents.

Uses

Used in Medicinal Chemistry:
Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis used as a chemical intermediate for the synthesis of various pharmaceutical agents. Its unique structure allows for the development of compounds with potential therapeutic applications.
Used in Drug Discovery:
Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis utilized in drug discovery as a lead compound for the identification of novel therapeutic agents. Its structural features may contribute to the design of new drugs with improved efficacy and selectivity.
Used in Research:
Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis employed in research studies to investigate the biological and pharmacological properties of imidazo[1,2-a]pyridine derivatives. This helps in understanding their potential use in the development of new pharmaceutical agents and contributes to the advancement of medicinal chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis used as a key building block for the synthesis of drug candidates. Its unique structural features enable the development of innovative therapeutic agents with improved pharmacological properties.
Used in Chemical Synthesis:
Imidazo[1,2-a]pyridine-3-acetonitrile, 2-phenylis utilized in chemical synthesis for the preparation of various imidazo[1,2-a]pyridine derivatives. These derivatives may exhibit diverse biological activities and can be further optimized for specific therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 885272-84-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 885272-84:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*2)+(2*8)+(1*4)=214
214 % 10 = 4
So 885272-84-4 is a valid CAS Registry Number.

885272-84-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-phenylimidazo[1,2-a]pyridin-3-yl)acetonitrile

1.2 Other means of identification

Product number -
Other names Imidazo[1,2-a]pyridine-3-acetonitrile,2-phenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885272-84-4 SDS

885272-84-4Downstream Products

885272-84-4Relevant articles and documents

Synthesis of C3-Cyanomethylated Imidazo[1,2- a ]pyridines via Ultrasound-Promoted Three-Component Reaction under Catalyst- and Oxidant-Free Conditions

Wu, Qingguo,Yang, Haifeng,Zhang, Jian,Zhang, Jie,Zhang, Yufeng

supporting information, p. 264 - 268 (2022/02/05)

An efficient synthesis of C3-cyanomethylated imidazo[1,2-α]pyridines via ultrasound-promoted three-component reaction under catalyst-free, oxidant-free, and mild conditions has been developed. A series of C3-cyanomethylated imidazo[1,2-α]pyridines were rapidly prepared with satisfactory yields and good functional group compatibility. This strategy cloud also be applied to the synthesis of zolpidem and alpidem in short steps.

Synthesis method of naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5, 6-diketone compound

-

Paragraph 0024-0066, (2020/07/02)

The invention discloses a synthetic method of a naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5, 6-diketone compound, which belongs to the technical field of organic chemistry. The synthesis method comprises the following steps: taking 2-aryl imidazo[1, 2-a] pyridine compound and diazonium acetonitrile as raw materials; synthesizing a 3-cyanomethylated imidazo[1, 2-a]pyridine compound 3 in the presence of a catalyst, reacting the compound 3 with an alcohol under the action of an acid to obtain an imidazo [1, 2-a] pyridine-3-acetate compound 4, and finally heating PPA to condense into a ring andsimutanously forms naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5,6-dione 5. The whole process of the method is carried out in the air, the used catalysts are common catalysts, the method is low in cost and environmentally friendly, the raw materials are easy to obtain, and a new synthesis path is provided for the compounds.

FeCl3-catalyzed C-3 functionalization of imidazo[1,2-a]pyridines with diazoacetonitrile under oxidant- and ligand-free conditions

Chen, Guang,Fan, Xuesen,Hu, Bing,Li, Bin,Zhang, Xinying

supporting information, (2020/03/04)

A facile synthesis of 2-(imidazo[1,2-a]pyridin-3-yl)acetonitriles via FeCl3-catalyzed site-selective C(sp2)-H alkylation of imidazo[1,2-a]pyridines with diazoacetonitrile is presented. This new method features with an environmentally benign catalyst, easily obtainable substrates, and oxidant- and ligand-free reaction conditions. Moreover, the importance of the products thus obtained is showcased by their ready transformation into some synthetically and pharmaceutically interesting products with good efficiency.

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