885273-64-3 Usage
Uses
Used in Pharmaceutical Industry:
3-(2-BROMO-PHENYL)-ISOXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is used as a building block for the synthesis of pharmaceutical compounds due to its diverse biological activities and potential reactivity.
Used in Agrochemical Industry:
3-(2-BROMO-PHENYL)-ISOXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is used as a precursor in the development of new agrochemical compounds, leveraging its potential reactivity and structural features.
Used in Organic Synthesis:
3-(2-BROMO-PHENYL)-ISOXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER is used as a starting material in organic synthesis, enabling the creation of various complex organic molecules for different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 885273-64-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 885273-64:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*3)+(2*6)+(1*4)=213
213 % 10 = 3
So 885273-64-3 is a valid CAS Registry Number.
885273-64-3Relevant academic research and scientific papers
Kadam, Kishorkumar S.,Gandhi, Thirumanavelan,Gupte, Amol,Gangopadhyay,Sharma, Rajiv
, p. 3996 - 4008 (2016)
An efficient, one-pot approach has been described for the synthesis of 3,5-disubstituted isoxazoles from substituted aldoximes (mixture of E and Z) and alkynes, using alkyl nitrites under conventional heating conditions. The key nitrile oxide intermediates that are required for the synthesis of isoxazoles are formed by treatment of substituted aldoxime with either tert-butyl nitrite or isoamyl nitrite. The generated nitrile oxides underwent in situ [3+2] dipolar cycloaddition to the substituted alkynes to give 3,5-disubstituted isoxazoles regioselectively in high to excellent yields. The developed synthetic methodology was applied for the synthesis of a previously reported potent hDGAT1 inhibitor.
