885274-99-7

Usage

Uses

Used in Medicinal Chemistry:
5-PHENYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is used as a building block for the synthesis of various pharmaceutical drugs and bioactive compounds due to its stable and versatile molecular structure.
Used in Drug Discovery:
In the field of drug discovery, 5-PHENYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is utilized as a potential candidate for the development of new drugs targeting diseases such as cancer, neurological disorders, and infectious diseases, owing to its unique molecular properties and structure.
Used in Pharmaceutical Industry:
5-PHENYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is used as a key intermediate in the synthesis of complex drug molecules, contributing to the advancement of novel therapeutic agents for the treatment of various medical conditions.

InChI:InChI=1/C17H23NO4/c1-17(2,3)22-16(21)18-10-13(9-14(11-18)15(19)20)12-7-5-4-6-8-12/h4-8,13-14H,9-11H2,1-3H3,(H,19,20)

Upstream product

• 98-80-6 phenylboronic acid 
• 939412-04-1 5-phenylpiperidine-3-carboxylic acid methyl ester 
• 10177-13-6 methyl 5-phenylpyridine-3-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 29681-44-5 5-bromo-3-pyridine carboxylic acid methyl ester 

Downstream Products

• 1353246-65-7 5-phenyl-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)piperidine-3-carboxamide 
• 1353254-49-5 tert-butyl 3-phenyl-5-(3-(pyridin-4-yl)-1-trityl-1H-indazol-5-ylcarbamoyl)piperidine-1-carboxylate 

Relevant academic research and scientific papers

CASPASE 6 INHIBITORS AND USES THEREOF

Disclosed herein, inter alia, are compounds and methods for inhibiting Caspase 6 and the treatment of diseases. Provided is a method of treating a neurodegenerative disease, the method including administering to a subject in need thereof an effective amou

LOX ENZYME INHIBITING METHODS AND COMPOSITIONS

This invention relates to compounds, pharmaceutical compositions and their use for treating fibrotic disorders, proliferative disorders, cardiovascular diseases, acute and chronic inflammatory disorders, primary and metastatic cancer, pulmonary conditions, ocular diseases, or neurological and neuropsychiatric conditions. One particular aspect of the inventions relates to inhibitors of the family of lysyl oxidase enzymes and their use as therapeutics for fibrotic disorders.

1,5-Substituted nipecotic amides: Selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability

The first highly potent and selective PDE8 inhibitors are disclosed. The initial tetrahydroisoquinoline hit was transformed into a nipecotic amide series in order to address a reactive metabolite issue. Reduction of lipophilicity to address metabolic liab