885313-12-2Relevant academic research and scientific papers
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole
Ishida, Tomio,Suzuki, Takayoshi,Hirashima, Shintaro,Mizutani, Kenji,Yoshida, Atsuhito,Ando, Izuru,Ikeda, Satoru,Adachi, Tsuyoshi,Hashimoto, Hiromasa
, p. 1859 - 1863 (2006)
A series of 1-cycloalkyl-2-phenyl-1H-benzimidazole-5-carboxylic acid derivatives was synthesized and evaluated for inhibitory activity against HCV NS5B RNA-dependent RNA polymerase (RdRp). A SAR study was performed and led to identify the 2-[(4-diarylmeth
