Bioorganic and Medicinal Chemistry Letters p. 1859 - 1863 (2006)
Update date:2022-08-05
Topics:
Ishida, Tomio
Suzuki, Takayoshi
Hirashima, Shintaro
Mizutani, Kenji
Yoshida, Atsuhito
Ando, Izuru
Ikeda, Satoru
Adachi, Tsuyoshi
Hashimoto, Hiromasa
A series of 1-cycloalkyl-2-phenyl-1H-benzimidazole-5-carboxylic acid derivatives was synthesized and evaluated for inhibitory activity against HCV NS5B RNA-dependent RNA polymerase (RdRp). A SAR study was performed and led to identify the 2-[(4-diarylmeth
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