885334-56-5Relevant articles and documents
Bis-imidazoles as molecular probes for peripheral sites of the zinc endopeptidase of botulinum neurotoxin serotype A
Merino, Isidro,Thompson, Jason D.,Millard, Charles B.,Schmidt, James J.,Pang, Yuan-Ping
, p. 3583 - 3591 (2006)
Botulinum neurotoxin serotype A (BoNTA) is highly toxic, and its antidote is currently unavailable. The essential light-chain subunit of BoNTA is a zinc endopeptidase that can be used as a target for developing antidotes. However, the development of high-