116754-58-6

Basic information

• Product Name: 13-BROMO-1-TRIDECANOL
• Synonyms: 13-BROMO-1-TRIDECANOL;13-BROMO-TRIDECAN-1-OL;1-Tridecanol, 13-bromo-
• CAS NO: 116754-58-6
• Molecular Formula: C₁₃H₂₇BrO
• Molecular Weight: 279.26
• Mol File: 116754-58-6.mol
• Article Data: 17

Chemical Properties

• Melting Point: 59 °C
• Boiling Point: 338°C at 760mmHg
• Flash Point: 128.8°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 6.87E-06mmHg at 25°C
• Refractive Index: 1.475
• Storage Temp.: 2-8°C
• PKA: 15.20±0.10(Predicted)
• CAS DataBase Reference: 13-BROMO-1-TRIDECANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 13-BROMO-1-TRIDECANOL(116754-58-6)
• EPA Substance Registry System: 13-BROMO-1-TRIDECANOL(116754-58-6)

Safety Data

• Hazardous Substances Data: 116754-58-6(Hazardous Substances Data)

Usage

Uses

13-Bromo-1-tridecanol is used in the synthesis of quinol fatty alcohols (QFA) which shows a very potent activity on axonal growth.

InChI:InChI=1/C13H27BrO/c14-12-10-8-6-4-2-1-3-5-7-9-11-13-15/h15H,1-13H2

Upstream product

• 13362-52-2 1,13-tridecanediol 
• 16339-75-6 12-tridecenyl alcohol 
• 80982-86-1 methyl ω-bromotridecanoate 
• 4101-68-2 1,10-dibromodecane 
• 105-95-3 1,4-dioxa-cycloheptadecane-5,17-dione 
• 151277-05-3 (E)-13-Bromo-tridec-2-enoic acid methyl ester 
• 70326-40-8 11-bromoundecan-1-al 
• 1611-56-9 1-Bromo-11-hydroxyundecane 
• 1472-87-3 dimethyl 1,11-undecanedicarboxylate 
• 505-52-2 brassylic acid 
• 116452-11-0 2-(13-Bromo-tridec-2-ynyloxy)-tetrahydro-pyran 

Downstream Products

• 4617-33-8 15-hydroxylpentadecanoic acid 
• 15462-16-5 13-bromotridecanoic acid 
• 338389-14-3 1-(14-hydroxytetradecyl-1-phenylsulfonyl)-2,6,6-trimethyl-1-cyclohexene 
• 56554-89-3 (Z)-14-Octadecenal 
• 56554-89-3 (E)-14-Octadecenal 
• 75912-18-4 24-hydroxytetracosanoic acid 
• 131105-35-6 p-nitrophenyl 24-linoleoxytetracosanoate 
• 885334-56-5 toluene-4-sulfonic acid 13-bromo-tridecyl ester 
• 887604-02-6 (((13-bromotridecyl)oxy)methyl)benzene 
• 887604-25-3 15-(2,5-dimethoxyphenyl)pentadecan-1-ol 
• 13266-02-9 n-tridecyltriphenylphosphonium bromide 
• 693-71-0 (13Z)-octadec-13-enoic acid 
• 1193721-67-3 22,22,22-d₃-docosanoic acid 
• 1393347-22-2 3-(13-[tert-butoxycarbonyl(2-cyanoethyl)amino]tridecyl)-1-(2,4-dinitrophenyl)pyridinium chloride 

Relevant articles and documents

A Synthetic Route to the MT1-MMP Inhibitor Ancorinoside D

A methyl ester of ancorinoside D, a 3-acyltetramic acid metabolite of a sponge Penares sollasi, was synthesised in ten steps starting from a protected β- d -glucopyranosyl-(1→4)- d -galactopyranosyltrichloroacetimidate donor. Its attachment to the left half of the 3-acyl spacer by a Schmidt glycosylation, 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-mediated oxidation to the uronic acid, introduction of the Z -alkene via Wittig reaction, and functionalisation of the spacer terminus with Meldrum's acid gave a β-keto ester that reacted with dimethyl N -methyl- d -aspartate under neutral conditions to afford a fully protected ancorinoside D as the product of an unusual domino N -acylation-Dieckmann condensation. Global deprotection left a methyl ester of ancorinoside D, which resisted all saponification attempts.

Method for synthesizing Micromelalopha troglodyta sex pheromone active ingredient

The invention relates to the technical field of insect sex pheromone component synthesis, and provides a novel method for synthesizing Micromelalopha troglodyta sex pheromone active ingredient. According to the novel method, 1, 13-tridecanol is used as an

METABOLICALLY STABLE PRODRUGS

Provided are prodrugs of various therapeutic agents that provide enhanced bioavilabilty of the therapeutic agent, and methods of treatment conditions in a subject by administration of the one or prodrugs. As provided herein a prodrug includes a therapeutic agent covalently attached to a cap, the cap having a structure according to formula (I) where: R1 is a branched or linear substituted or unsubstituted C2-C6 alkyl, alkenyl, or alkynl; X is -S(0)2-; R2 is a branched or linear substituted or unsubstituted C4-C20 alkyl, alkenyl, or alkynyl; and R3 is -H, C3-C5 cycloalkyl, C3-C5 cycloheteroalkyl, -C(CH3)3, -CF3, -C(CF3)3, or a substituted or unsubstituted phenyl.