885357-46-0

Basic information

• Product Name: L-Aspartic acid, 3-(phenylmethyl)-N-(triphenylmethyl)-, dimethyl ester
• CAS NO: 885357-46-0
• Molecular Formula: C32H31NO4
• Molecular Weight: 493.602
• Mol File: 885357-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, 3-(phenylmethyl)-N-(triphenylmethyl)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, 3-(phenylmethyl)-N-(triphenylmethyl)-, dimethyl ester(885357-46-0)
• EPA Substance Registry System: L-Aspartic acid, 3-(phenylmethyl)-N-(triphenylmethyl)-, dimethyl ester(885357-46-0)

Safety Data

• Hazardous Substances Data: 885357-46-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 116393-72-7 dimethyl (2S)-N-(triphenylmethyl)aspartate 

Downstream Products

• 871123-98-7 (2S,3R)-β-benzylaspartic acid 
• 871123-98-7 L-threo-β-benzylaspartic acid 

Relevant articles and documents

3-alkylaryl aspartate compounds and their use for selective enhancement of synaptic transmission

The present invention provides an L-aspartate derivative compound represented by the following structure wherein Ar represents an aromatic group; L represents a linking moiety; R represents hydrogen, alkyl, aryl, or heteroaryl; and indicates that the stereochemistry at the 3-position can be R or S. The compounds of the invention are useful for selectively inhibiting EAAT3 and for enhancing synaptic transmission. Additionally, the inventive compounds can be used to treat a patient suffering from Alzheimers disease or a neuropathy or a neurodegenerative disease in which L-glutamate transporter activity is involved in the onset of the disease.