885462-53-3Relevant academic research and scientific papers
Access to phosphacymantrene-2-carboxylic acid and 2-carboxaldehyde derivatives
Deschamps, Bernard,Ricard, Louis,Mathey, Fran?ois
, p. 5688 - 5690 (1999)
Two new approaches to α-functional phosphacymantrenes are described. The reaction of [Mn2(CO)10] with a phosphole-2-carboxylate affords the corresponding phosphacymantrene2-carboxylate 2. Replacing one carbonyl by one triphenylphosphine on manganese enhances the reactivity of phosphacymantrenes toward electrophilic substitution. Thus, a Vilsmeier formylation leading to a phosphacymantrene-2-carboxaldehyde such as 5 becomes possible. The reduction of 5 affords the corresponding primary alcohol 6 and the methyl derivative 7.
