885482-95-1

Upstream product

• 109-01-3 1-methyl-piperazine 
• 846023-51-6 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-iodo-6-methoxy-3-quinolinecarbonitrile 
• 388121-83-3 3-(N-methylpiperazino)-prop-1-yne 
• 885482-99-5 4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-hydroxy-but-1-ynyl)-6-methoxyquinoline-3-carbonitrile 
• 364793-73-7 3-cyano-4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxyquinolin-7-yl trifluoromethanesulfonate 

Relevant academic research and scientific papers

Inhibition of Src kinase activity by 7-ethynyl-4-phenylamino-3-quinolinecarbonitriles: Identification of SKS-927

Of a series of 7-ethynyl-3-quinolinecarbonitriles, the most potent Src inhibitory activity was observed with 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[4-(4-methylpiperazi n-1-yl)but-1-ynyl]-3-quinolinecarbonitrile (SKS-927). Variation of the so

4 [(2,4-DICHLORO-5-METHOXYPHENYL)AMINO]-6-ALKOXY-7-ETHYNYL-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF ISCHEMIC INJURY

This invention relates to compounds of the formula (I): wherein: R is methyl or ethyl; R' and R" are independently alkyl of 1 to 3 carbon atoms, or R' and R", taken together with the nitrogen to which they are attached, can form a 5 or 6 membered saturate