885503-47-9

Upstream product

• 885503-46-8 (2R,3R)-2-(tert-butyldiphenylsilanyloxymethyl)-3-isobutyl-5-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 556-56-9 allyl iodid 

Downstream Products

• 885503-51-5 (2R,3R,4R,5R)-2-[(1S)-tert-butoxycarbonyl-2-phenylethylcarbamoyl]-5-(dimethoxyphosphoryl)-4-[2-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)ethyl]-3-isobutylpyrrolidine-1-carboxylic acid tert-butyl ester 
• 885503-52-6 (2R,3R,4R,5R)-5-(dimethoxyphosphoryl)-4-[2-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)ethyl]-2-[(1S)-methoxycarbonyl-3-phenylpropylcarbamoyl]-3-isobutylpyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Design and synthesis of diversely substituted azacyclic inhibitors of endothelin converting enzyme

A series of azacyclic phosphonic acids were synthesized from L-pyroglutamic acid, 6-oxo-L-pipecolic acid, and their enantiomers. The objective was to study the effect of constraining acyclic inhibitors of endothelin converting enzyme on inhibitory activit