885518-47-8

Basic information

• Product Name: Methyl 4-bromo-6-(1H)-ind...
• Synonyms: Methyl 4-bromo-6-(1H)-ind...;Methyl 4-broMo-1H-indazole-6-carboxylate;Methyl 4-broMo-6-(1H)-indazole carboxylate;1H-Indazole-6-carboxylicacid,4-broMo-,Methylester;4-BroMo-1H-indazole-6-carboxylic acid Methyl ester
• CAS NO: 885518-47-8
• Molecular Formula: C₉H₇BrN₂O₂
• Molecular Weight: 255.06808
• Mol File: 885518-47-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 395.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.709
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.21±0.40(Predicted)
• CAS DataBase Reference: Methyl 4-bromo-6-(1H)-ind...(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-bromo-6-(1H)-ind...(885518-47-8)
• EPA Substance Registry System: Methyl 4-bromo-6-(1H)-ind...(885518-47-8)

Safety Data

• Hazardous Substances Data: 885518-47-8(Hazardous Substances Data)

Usage

General Description

Methyl 4-bromo-6-(1H)-indazole-1-carboxylate is a chemical compound that belongs to the indazole class. It is characterized by the presence of a methyl group, a bromine atom, and a carboxylate group attached to a 6-membered ring of the indazole molecule. Methyl 4-bromo-6-(1H)-ind... has potential applications in the fields of organic synthesis and pharmaceutical research due to its unique structure and reactivity. Its properties and uses also make it an important intermediate in the production of various drugs and other organic compounds. Additionally, it may have biological activities and pharmacological effects that could make it valuable for further study and potential medical applications.

Upstream product

• 223519-11-7 methyl 3-amino-5-bromo-4-methylbenzoate 
• 882679-96-1 methyl 4-bromo-1H-indole-6-carboxylate 
• 223519-08-2 methyl 3-bromo-4-methyl-5-nitrobenzoate 
• 34545-20-5 3-bromo-4-methyl-5-nitro-benzoic acid 
• 96-98-0 4-methyl-3-nitrobenzoic acid 

Downstream Products

• 1285532-20-8 C₂₁H₂₅N₅O 
• 1285531-68-1 1-(4-(6-(N-(2-(piperidin-1-yl)ethyl)aminocarbonyl)-1H-indazol-4-yl)phenyl)-3-(3-(trifluoromethoxy)phenyl)urea 
• 885523-43-3 4-bromo-1H-indazole-6-carboxylic acid 
• 885518-53-6 4-bromo-1H-indazol-6-amine 
• 1527007-77-7 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate 
• 170487-40-8 1H-indazole-6-carboxylic acid methyl ester 
• 1638772-21-0 methyl 4-bromo-2-methyl-2H-indazole-6-carboxylate 
• 1638759-79-1 methyl 4-bromo-1-methyl-1H-indazole-6-carboxylate 

Relevant articles and documents

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The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell pr

Synthesis of substituted 4-(1H-indol-6-yl)-1H-indazoles as potential PDK1 inhibitors

The development of a preparative route to a series of novel 4-(1H-indol-6-yl)-1H-indazole compounds as potential PDK1 inhibitors is described. The synthetic strategy centres on the late-stage Suzuki cross-coupling of N-unprotected indazole and indole frag