885519-07-3

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-2-methoxy-6-nitrotoluene is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Bromo-2-methoxy-6-nitrotoluene is utilized as a precursor in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Dye Industry:
4-Bromo-2-methoxy-6-nitrotoluene is employed as a building block in the synthesis of dyes, contributing to the development of a wide range of colorants used in various industries, including textiles and plastics.
Used in Research and Development:
This chemical compound is also used in research and development processes, where it serves as a valuable tool for scientists to explore new chemical reactions and syntheses, potentially leading to innovative products and applications.
Safety Note:
It is important to handle 4-Bromo-2-methoxy-6-nitrotoluene with care, as it may pose health risks if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken during its use to minimize potential hazards.

Upstream product

• 864550-40-3 5-bromo-2-methyl-3-nitroaniline 
• 95192-64-6 5-bromo-2-methyl-1,3-dinitrobenzene 
• 606-20-2 2,6-dinitrotoluene 
• 864550-41-4 5-bromo-2-methyl-3-nitrophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 1082040-45-6 5-bromo-3-methoxy-2-methylaniline 
• 393553-57-6 6-bromo-4-methoxyindole 

Relevant academic research and scientific papers

A Concise Total Synthesis of Breitfussin A and B

(Chemical Equation Presented). The first total synthesis of breitfussin A and B is described. The approach features two palladium-catalyzed cross-couplings installing the indole and pyrrole onto the oxazole core and selective lithiation/iodination of a common indole-oxazole fragment providing 2,4-diiodinated or 2-iodinated oxazoles as potential precursors for breitfussin A and B, respectively. An unexpected acid promoted deiodination was utilized in the synthesis of breitfussin B. Comparison of the synthetic material with previously reported spectral data of isolated breitfussin A and B verified the structure of the breitfussin framework.

2-AMINOQUINAZOLINE DERIVATIVE

An object of the present invention is to provide compounds which are useful as protein kinase inhibitors. Disclosed is a 2-aminoquinazoline derivative represented by the following formula (I): wherein R1 represents a lower alkyl group which may be substituted with a halogen atom, or a halogen atom; R2 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a halogen atom, a hydroxyl group, a substituted or unsubstituted lower alkoxy group, a substituted or unsubstituted amino group, a substituted or unsubstituted acylamino group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, or a substituted or unsubstituted lower alkylureido group; and X, Y and Z each independently represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a halogen atom, a hydroxyl group, a carboxyl group, a lower alkoxycarbonyl group, a cyano group, a carbamoyl group, a substituted or unsubstituted lower alkoxy group, a substituted or unsubstituted amino group, a substituted or unsubstituted lower alkoxycarbonylamino group, a substituted or unsubstituted lower alkylaminocarbonyl group, a lower alkylsulfonylamino group, a substituted or unsubstituted lower alkylureido group, or a substituted or unsubstituted acylamino group, or X and Y may be combined to form a 5- to 6-membered ring forming a bicyclic fused ring, wherein the 5- to 6-membered ring may optionally have a substituent, provided that when X and Y are not combined to form a fused ring, R2 represents a hydrogen atom and, when X and Y are combined to form a fused ring, a saturated or unsaturated, bicyclic alicyclic or heterocyclic fused ring can be formed.