393553-57-6 Usage
General Description
6-Bromo-4-methoxyindole is a chemical compound with the molecular formula C9H8BrNO. It is an indole derivative with a bromine atom at the 6th position and a methoxy group at the 4th position. 6-BROMO-4-METHOXYINDOLE is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used in research and development as a reagent in organic and medicinal chemistry. 6-Bromo-4-methoxyindole has potential applications in the development of new drugs and can also be used as a starting material for the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 393553-57-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,3,5,5 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 393553-57:
(8*3)+(7*9)+(6*3)+(5*5)+(4*5)+(3*3)+(2*5)+(1*7)=176
176 % 10 = 6
So 393553-57-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H8BrNO/c1-12-9-5-6(10)4-8-7(9)2-3-11-8/h2-5,11H,1H3
393553-57-6Relevant articles and documents
C4?H alkoxylation of 6-bromoindole and its application to the synthesis of breitfussin B
Nabi, Ardalan A.,Liyu, Jessica,Lindsay, Ashley C.,Sperry, Jonathan
, p. 1199 - 1202 (2018)
Subjecting 6-bromoindole to an iridium-catalysed triborylation-diprotodeborylation sequence followed by Chan-Evans-Lam coupling gives 6-bromo-4-methoxyindole in good overall yield. This indole C4?H alkoxylation process was used in a formal synthesis of the natural product breitfussin B.
Synthesis of Breitfussin B by Late-Stage Bromination
Khan, Akbar H.,Chen, Jason S.
supporting information, p. 3718 - 3721 (2015/08/18)
The breitfussins are halogenated natural products whose structures were determined with the assistance of atomic-force microscopy. The site selectivity of N-bromosuccinimide-mediated bromination of a model breitfussin core was found to be strongly depende